Yoram Yasur Blume: What is kidney failure?

Yoram Yasur Blume | Kidney failure means the failure of the kidney homeostatic mechanisms.

Functional elasticity and kidney accommodation capacity allow maintenance. Of homeostasis through a wide variability of the physicochemical characters of urine.

Both are lost gradually or abruptly with the disease.

The kidney becomes unable to perform their work or does it incompletely.

Each time within more narrow limits, with no possibility of variability.

In either case there is said to be a kidney failure.


Types of kidney failure and its symptoms:


According to their mode of presentation, both abrupt and sudden, or conversely, slow and progressive, renal failure can be acute (ARF) or chronic (IRC) respectively:

Acute renal failure (ARF) is defined as the sudden and prolonged the cessation of kidney function. With a resulting disorder in urine formation and regulation of the internal environment.

It is manifested by severe oligoanuria syndrome (polyuria), azotemia and humoral and hemodynamic imbalances.

Acute renal failure is a complication of many diseases. In addition this situation can occur in all ages of life, from newborns to the elderly.

And whose most prominent character is its potential reversibility.

“The full picture of acute renal failure can occur without there being any anatomical alteration of the kidneys or urinary tract.

And ultimately due to insufficient blood supply to the kidney (renal hypoperfusion).

Besides bilateral and extensive injury of the parenchymal or obstruction of the urinary tract.

Chronic renal failure (CRF) is the gradual, progressive and fatal failure of kidney homeostatic mechanisms.

Gradual means that in different evolutionary stages, kidney failure has a greater or lesser extent.

Progressive indicates that in the beginning, the failure is minimal, but with the persistence of the disease worsening inexorably.

Fatal points means an ultimately ineffective therapy. Since it is purely symptomatic or pathogenic.

And is only permanently operative in the case of being etiological on nephropathy renal failure produced.

Diagnosis and treatment of renal failure:

In itself, chronic renal failure is not a disease but a humoral clinical syndrome that accompanies numerous kidneys, extra renal and systemic diseases.

Latent, compensated, decompensated and terminal are the four evolutionary phases of the IRC, useful for understanding the pathophysiology.

The diagnosis of renal failure is done by measuring the glomerular filtration rate (GFR). Yoram Yasur Blume: “The results GFR of a blood test for creatinine, a waste product of muscle activity”.

If the GFR falls below 15, the patient has renal failure (chronic kidney disease stage 5). Also needs treatment to replace the function of their kidneys.

Besides If is less than 30, the physician and patient should discuss the possibility of starting a treatment.

In addition treatments used to treat kidney failure are hemodialysis, peritoneal dialysis or kidney transplantation.

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